Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repair
RNA-seq (gene expression) · mouse · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 7 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repairJCI insight · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE307419_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1321592 and SRA study SRP618237. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 7 replicated groups read from 26 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9223708 Col1-Sal Rep 1 Col1-Sal
- GSM9223709 Col1-Sal Rep 2 Col1-Sal
- GSM9223710 Col1-Sal Rep 3 Col1-Sal
- GSM9223711 aSMA-Sal1 Rep 1
- GSM9223712 aSMA-Sal2 Rep 2
- GSM9223713 aSMA-Sal3 Rep 3
- GSM9223714 Plin2-Sal1 Rep 1
- GSM9223715 Plin2-Sal2 Rep 2
- GSM9223716 Plin2-Sal3 Rep 3
- GSM9223717 Col1-Bleo 3wk Rep 1 Col1-Bleo 3wk
- GSM9223718 Col1-Bleo 3wk Rep 2 Col1-Bleo 3wk
- GSM9223719 Col1-Bleo 3wk Rep 3 Col1-Bleo 3wk
- GSM9223720 aSMA-Bleo 3wk Rep 1 aSMA-Bleo 3wk
- GSM9223721 aSMA-Bleo 3wk Rep 2 aSMA-Bleo 3wk
- GSM9223722 aSMA-Bleo 3wk Rep 3 aSMA-Bleo 3wk
- GSM9223723 Plin2-Bleo 3wk Rep 1 Plin2-Bleo 3wk
- GSM9223724 Plin2-Bleo 3wk Rep 2 Plin2-Bleo 3wk
- GSM9223725 Plin2-Bleo 3wk Rep 3 Plin2-Bleo 3wk
- GSM9223726 Col1-Bleo 8wk Rep 1 Col1-Bleo 8wk
- GSM9223727 Col1-Bleo 8wk Rep 2 Col1-Bleo 8wk
- GSM9223728 Col1-Bleo 8wk Rep 3 Col1-Bleo 8wk
- GSM9223729 aSMA-Bleo 8wk Rep 1 aSMA-Bleo 8wk
- GSM9223730 aSMA-Bleo 8wk Rep 2 aSMA-Bleo 8wk
- GSM9223731 aSMA-Bleo 8wk Rep 3 aSMA-Bleo 8wk
- GSM9223732 Plin2-Bleo 8wk Rep 1 Plin2-Bleo 8wk
- GSM9223733 Plin2-Bleo 8wk Rep 2 Plin2-Bleo 8wk
- GSE338894 An orally active, gut-enriched AhR agonist demonstrates therapeutic efficacy in colitis through regulation of inflammation, barrier homeostasis, and fibrosis 50 samples shares demonstrate, enriched, fibrosis
- GSE262420 Mechanomemory of pulmonary fibroblasts demonstrates reversibility of transcriptomics and contraction phenotypes 20 samples shares demonstrate, fibroblast, pulmonary
- GSE229916 Pericytes and perivascular fibroblasts contribute to central nervous system fibrosis in a region dependent manner 832 samples shares fibroblast, fibrosis
- GSE261166 Transcription factor 21 regulates cardiac myofibroblast formation and fibrosis [RNA-Seq] 16 samples shares fibroblast, fibrosis
- GSE273123 Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling (Bulk RNA-Seq) 16 samples shares fibroblast, fibrosis
- GSE289751 Resolution of inflammation in imprinted fibroblast-like synoviocytes establishes a transcriptomic signature that promotes endothelial cell dysfunction. 12 samples shares fibroblast, resolution
- GSE241176 Fibroblast-specific TGF-b signaling mediates dysfunction, fibrosis and hypertrophy in a mouse model of obesity-associated type 2 diabetes [RNA-seq: Smad3 in dbdb] 12 samples shares fibroblast, fibrosis
- GSE277789 Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution [Smart-seq3-RNA-seq-add] 830 samples shares resolution
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.