GEO series
The ErbB3 receptor tyrosine kinase regulates small intestinal barrier function and expression of the tight junctional protein Pmp22
GSE308942
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/12/01
GPL19057
Summary
We tested the role of ErbB3 in small intestinal permeability. Loss of ErbB3 in the intestinal epithelium results in increased intestinal permeability and reduced expression of Pmp22. Permeability induced by LPS can be reduced by administration of the ErbB3 ligand Nrg1.
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