Accessible chromatin profile of early life and adult origin B cell populations
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 26 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Early-life B cell memory is archived in the mouse B-1 cell compartment and drives chronic lymphocytic leukemia-like diseaseCell reports · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309960_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1364052 and SRA study SRP644566. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 8 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9285308 Spleen_FoB_Tpos_609 Spleen_FoB_Tpos
- GSM9285309 Spleen_FoB_Tneg_609 Spleen_FoB_Tneg
- GSM9285310 Spleen_MzB_Tpos_609 Spleen_MzB_Tpos
- GSM9285311 Spleen_MzB_Tneg_609 Spleen_MzB_Tneg
- GSM9285312 PerC_B1_Tpos_609 PerC_B1_Tpos
- GSM9285313 PerC_B1_Tneg_609 PerC_B1_Tneg
- GSM9285314 Spleen_FoB_Tpos_610 Spleen_FoB_Tpos
- GSM9285315 Spleen_FoB_Tneg_610 Spleen_FoB_Tneg
- GSM9285316 Spleen_MzB_Tpos_610 Spleen_MzB_Tpos
- GSM9285317 Spleen_MzB_Tneg_610 Spleen_MzB_Tneg
- GSM9285318 PerC_B1_Tpos_610 PerC_B1_Tpos
- GSM9285320 PerC_B1_Tneg_610 PerC_B1_Tneg
- GSM9285323 PP_MBC_Tpos_610 PP_MBC_Tpos
- GSM9285327 PP_MBC_Tneg_610 PP_MBC_Tneg
- GSM9285330 PerC_B1_Tpos_611 PerC_B1_Tpos
- GSM9285333 PerC_B1_Tneg_611 PerC_B1_Tneg
- GSM9285334 PP_MBC_Tpos_611 PP_MBC_Tpos
- GSM9285335 PP_MBC_Tneg_611 PP_MBC_Tneg
- GSM9285336 Spleen_FoB_Tpos_612 Spleen_FoB_Tpos
- GSM9285337 Spleen_FoB_Tneg_612 Spleen_FoB_Tneg
- GSM9285338 Spleen_MzB_Tpos_612 Spleen_MzB_Tpos
- GSM9285339 Spleen_MzB_Tneg_612 Spleen_MzB_Tneg
- GSM9285340 PerC_B1_Tpos_612 PerC_B1_Tpos
- GSM9285341 PerC_B1_Tneg_612 PerC_B1_Tneg
- GSM9285342 PP_MBC_Tpos_612 PP_MBC_Tpos
- GSM9285343 PP_MBC_Tneg_612 PP_MBC_Tneg
- GSE264193 H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [ChIP-seq] 57 samples shares chromatin, early
- GSE278416 3D Chromatin organization of signal-induced specific enhancers safeguards early ESC differentiation by promoting cluster gene expression 40 samples shares chromatin, early
- GSE295991 Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at meiotic promoters in mice 32 samples shares accessible, chromatin
- GSE279796 Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability 18 samples shares chromatin, adult
- GSE315771 HDI-STARR-seq library profiling of differential accessible chromatin regions (DARs) in livers of male, female and male treated with continuous growth hormone (cGH) mice. 12 samples shares accessible, chromatin
- GSE296438 Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at the promoters of genes expressed during meiosis [scRNA-seq & scATAC-seq] 10 samples shares accessible, chromatin
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares chromatin
- GSE272524 Chromatin-dependent motif syntax defines differentiation trajectories [ChIP-seq] 76 samples shares chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.