Uridine Modulates Gene Expression Programs During RANKL-Induced Osteoclastogenesis in RAW264.7 Cells
RNA-seq (gene expression) · mouse · 9 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 9 samples: 3 × Ctrl vs 3 × RANKL vs 3 × UDRANKLGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE311708_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1370289. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 9 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9330096 Ctrl1 Ctrl
- GSM9330097 Ctrl2 Ctrl
- GSM9330098 Ctrl3 Ctrl
- GSM9330099 RANKL1 RANKL
- GSM9330100 RANKL2 RANKL
- GSM9330101 RANKL3 RANKL
- GSM9330102 UDRANKL_1 UDRANKL
- GSM9330103 UDRANKL_2 UDRANKL
- GSM9330104 UDRANKL_3 UDRANKL
- GSE311709 Transcriptomic Profiling of RAW264.7 Cells During RANKL-Induced Osteoclast Differentiation 6 samples shares raw264, rankl-induced
- GSE288599 Nuclear Paxillin Modulates Alternative Splicing Programs in Neurons during Sensitive Periods of Brain Development 60 samples shares modulates, programs
- GSE290919 Transcriptome analysis of Kdm7a-deficient RAW264.7 cells during macrophage polarization. 18 samples shares raw264
- GSE318498 Gene expression differences between LPS, anti-CD36 Abs, or LPS plus anti-CD36 Abs treated RAW264.7 cells. 12 samples shares raw264
- GSE252673 The Transcriptome of MHV or PVM Infected RAW264.7 Cell 45 samples shares raw264
- GSE279383 Transcriptome profiles of RAW264.7 cells under fibroblast coculture with or without LPS sitimulation and tryptophan metabolites intervention 24 samples shares raw264
- GSE248235 Immunoregulation of Raw264.7 by Nitrate in vitro 24 samples shares raw264
- GSE287433 Effects of Tirzepatide on macrophage polarization, inflammatory factors and atherosclerotic genes in RAW264.7 cells under oxidative low-density lipoprotein 16 samples shares raw264
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.