Cell-specific effects of acute sleep deprivation on transcriptomic signatures of non-neuronal cells in the mouse hippocampus and prefrontal cortex
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 3 × PFC, non sleep deprived male mice vs 3 × PFC, sleep deprived male mice vs 2 × HPC, non sleep deprived male mice vs 2 × HPC, sleep deprived male miceGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cell-specific effects of acute sleep deprivation on transcriptomic signatures of non-neuronal cells in the mouse hippocampus and prefrontal cortexbioRxiv : the preprint server for biology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE313497_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1379655 and SRA study SRP654584. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 4 replicated groups read from 11 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9368988 HPC, non sleep deprived male mice 1 HPC, non sleep deprived…
- GSM9368989 HPC, non sleep deprived male mice 2 HPC, non sleep deprived…
- GSM9368990 HPC, sleep deprived male mice 1 HPC, sleep deprived mal…
- GSM9368991 HPC, sleep deprived male mice 2 HPC, sleep deprived mal…
- GSM9368992 PFC, non sleep deprived male mice 1 PFC, non sleep deprived…
- GSM9368993 PFC, non sleep deprived male mice 2 PFC, non sleep deprived…
- GSM9368994 PFC, non sleep deprived male mice 3 PFC, non sleep deprived…
- GSM9368995 PFC, sleep deprived male mice 1 PFC, sleep deprived mal…
- GSM9368996 PFC, sleep deprived male mice 2 PFC, sleep deprived mal…
- GSM9368997 PFC, sleep deprived male mice 2R
- GSM9368998 PFC, sleep deprived male mice 3 PFC, sleep deprived mal…
- GSE307546 Transcriptomics Analysis of bulk RNA from dissected brain regions (medial prefrontal cortex, cerebellum, and hippocampus) from 129/Sv-Cyp2e1tm1Gonz/J (CYP2E1-KO) and 129S1/SvImJ (WT) mice 48 samples shares hippocampus, prefrontal, cortex
- GSE331524 Transcriptomic analysis of hippocampus and prefrontal cortex in a mouse model of chronic radiation-induced gastrointestinal injury 12 samples shares hippocampus, prefrontal, cortex
- GSE306583 Developmental trajectory of the mouse transcriptome following placental allopregnanolone insufficiency in the somatosensosry cortex, hippocampus and cerebellum 175 samples shares hippocampus, cortex
- GSE292221 Brain transcriptome analysis in the cortex and hippocampus of Cyfip2 Arg87Cys knock-in mice at four different postnatal stages 64 samples shares hippocampus, cortex
- GSE316731 Endothelial Cell-specific Activation of NOX1 Drives Obesity and Metabolic Syndrome via Skeletal Muscle Mitochondrial Dysfunction with Novel Genetic Signatures 12 samples shares cell-specific, signatures
- GSE299158 Acute Sleep Deprivation Accelerates Brain Endothelial Cell Senescence and Functional Changes of Endothelial Cells in Mice 12 samples shares deprivation, acute
- GSE288262 B-cell-Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Pro-Inflammatory Signatures in a Myeloma Mouse Model 10 samples shares cell-specific, signatures
- GSE333807 Single-nucleus multiomic profiling of hippocampus and frontal cortex in a C9orf72 knockout mouse model 52 samples shares hippocampus, cortex
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.