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The function of α7nAChR in skeletal muscle.

GSE315922 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/30 Platform GPL24247
Summary
We found that Chrna7 is involved in regulating cellular mitochondrial metabolism and maintaining the FOXO1 signaling pathway in skeletal muscle, thereby influencing muscle cell atrophy and regeneration.
Published in
Activation of α7nAChR reduces inflammation and apoptosis, promoting muscle regeneration through the AKT-FOXO1 pathway
Jin X, Zhou Y, Sun L et al. · Cell death and differentiation 2026 · PMID 41933047 · doi:10.1038/s41418-026-01738-1
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Also filed as BioProject PRJNA1399956 and SRA study SRP660668. Searching any of these in the dataset finder brings you back here.

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