Bulk RNA-seq detects cMPC HO signature in hip arthroplasty patients
RNA-seq (gene expression) · human · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 22 samples: 12 × HOneg_Patient vs 10 × HOpos_PatientGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Early detection of aberrant cell fate and repair using circulating progenitor cells in patients with heterotopic ossificationNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE316836_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1404336 and SRA study SRP663913. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 2 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9460854 HOneg_Patient_1 HOneg_Patient
- GSM9460855 HOneg_Patient_2 HOneg_Patient
- GSM9460856 HOneg_Patient_3 HOneg_Patient
- GSM9460857 HOneg_Patient_4 HOneg_Patient
- GSM9460858 HOneg_Patient_5 HOneg_Patient
- GSM9460859 HOneg_Patient_6 HOneg_Patient
- GSM9460860 HOneg_Patient_7 HOneg_Patient
- GSM9460861 HOneg_Patient_8 HOneg_Patient
- GSM9460862 HOneg_Patient_9 HOneg_Patient
- GSM9460863 HOneg_Patient_10 HOneg_Patient
- GSM9460864 HOneg_Patient_11 HOneg_Patient
- GSM9460865 HOneg_Patient_12 HOneg_Patient
- GSM9460866 HOpos_Patient_1 HOpos_Patient
- GSM9460867 HOpos_Patient_2 HOpos_Patient
- GSM9460868 HOpos_Patient_3 HOpos_Patient
- GSM9460869 HOpos_Patient_4 HOpos_Patient
- GSM9460870 HOpos_Patient_5 HOpos_Patient
- GSM9460871 HOpos_Patient_6 HOpos_Patient
- GSM9460872 HOpos_Patient_7 HOpos_Patient
- GSM9460873 HOpos_Patient_8 HOpos_Patient
- GSM9460874 HOpos_Patient_9 HOpos_Patient
- GSM9460875 HOpos_Patient_10 HOpos_Patient
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.