Erk3 deletion drives oxidative adaptations in skeletal muscle
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Erk3 deletion drives oxidative adaptations in skeletal muscleMolecular metabolism · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE319950_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1425585 and SRA study SRP678107. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9530212 siNTC_BSA_(1)
- GSM9530213 siNTC_BSA_(2)
- GSM9530214 siNTC_BSA_(3)
- GSM9530215 siErk3_BSA_(1)
- GSM9530216 siErk3_BSA_(2)
- GSM9530217 siErk3_BSA_(3)
- GSM9530218 siMk5_BSA_(1)
- GSM9530219 siMk5_BSA_(2)
- GSM9530220 siMk5_BSA_(3)
- GSM9530221 siNTC_Palmitic_(1)
- GSM9530222 siNTC_Palmitic_(2)
- GSM9530223 siNTC_Palmitic_(3)
- GSM9530224 siErk3_Palmitic_(1)
- GSM9530225 siErk3_Palmitic_(2)
- GSM9530226 siErk3_Palmitic_(3)
- GSM9530227 siMk5_Palmitic_(1)
- GSM9530228 siMk5_Palmitic_(2)
- GSM9530229 siMk5_Palmitic_(3)
- GSE329069 Deletion of P311 enhances regeneration in aged skeletal muscle 9 samples shares deletion, skeletal, muscle
- GSE294765 A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophy 35 samples shares adaptations, skeletal, muscle
- GSE274902 Mogat1 drives metabolic adaptations to evade immune surveillance 32 samples shares adaptations, drives
- GSE252120 Oxidative stress induced telomere instability/damage drives T cell dysfunction in cancer 32 samples shares oxidative, drives
- GSE311013 Elimination of myotonia improves myopathy in a muscleblind knockout model of myotonic dystrophy: longread sequencing of Clcn1 transcripts in muscle from Mbnl1 knockout, Exon 7a deletion, and ADR mice. 27 samples shares deletion, muscle
- GSE305242 Effects of Sphk1 deletion in smooth muscle cells on murine arterial transcriptome in hypertension 26 samples shares deletion, muscle
- GSE263262 The impact of TRF2 deletion on gene expression profile of muscle stem cells 16 samples shares deletion, muscle
- GSE305276 Osteocyte-specific deletion of Gasdermin D drives osteoarthritis cartilage degeneration by promoting inflammation and remodeling in subchondral bone 9 samples shares deletion, drives
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.