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Transcriptomic profiling of GATA4 Knock-Out in cardiac, lung, and tail tip fibroblasts

GSE325933 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/07/01 Platform GPL24247
Summary
Fibroblasts from different anatomical origins exhibit distinct phenotypic properties. In this study, we aimed to determine the cell-type-specific transcriptional responses to GATA4 overexpression. We performed bulk RNA-seq on cardiac fibroblasts (CF), lung fibroblasts (LF), and tail tip fibroblasts (TTF) transduced with either Ad-GFP (control) or Ad-Cre (GATA4 KO). The goal is to delineate the general versus source-specific GATA4 regulatory networks.
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Direct links to NCBI, no account and no request form: the whole study as GSE325933_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1442651 and SRA study SRP686480. Searching any of these in the dataset finder brings you back here.

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