IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 21 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 21 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE328307_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1454525 and SRA study SRP568331. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 21 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8831260 Blimp1_WT_mouse1 Blimp1_WT_mouse
- GSM8831261 Blimp1_WT_mouse2 Blimp1_WT_mouse
- GSM8831262 Blimp1_KO_mouse1 Blimp1_KO_mouse
- GSM8831263 Blimp1_KO_mouse2 Blimp1_KO_mouse
- GSM8831264 Blimp1_WT, mouse1 Blimp1_WT, mouse
- GSM8831265 Blimp1_WT, mouse2 Blimp1_WT, mouse
- GSM8831266 Blimp1_WT, mouse3 Blimp1_WT, mouse
- GSM8831267 Blimp1_KO, mouse1 Blimp1_KO, mouse
- GSM8831268 Blimp1_KO, mouse2 Blimp1_KO, mouse
- GSM8831269 Blimp1_KO, mouse3 Blimp1_KO, mouse
- GSM8831270 Unstim_mouse1 Unstim_mouse
- GSM8831271 Unstim_mouse2 Unstim_mouse
- GSM8831272 Unstim_mouse3 Unstim_mouse
- GSM8831273 Unstim_mouse4 Unstim_mouse
- GSM8831274 Stim_mouse1 Stim_mouse
- GSM8831275 Stim_mouse2 Stim_mouse
- GSM8831276 Stim_mouse3 Stim_mouse
- GSM8831277 Stim_mouse4 Stim_mouse
- GSM9463226 Lung Untreated
- GSM9463227 Lung Papain
- GSM9463228 Lung Alternaria
- GSE291231 IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma [RNA-seq] 14 samples shares blimp-1, il-9, lymphocytes, identity, allergic, protect, innate, asthma
- GSE283565 TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation 10 samples shares identity, allergic
- GSE313261 Global transcriptome analysis of IL-33, IL-25, IL-13, TSLP, IL-4, and IL-9 overexpression in mouse spleen 49 samples shares il-9
- GSE199288 Perivascular fibrosis is mediated by a KLF10-IL-9 signaling axis in CD4+ T cells 27 samples shares il-9
- GSE292222 Macrophage-intrinsic and IL-9-dependent arginine metabolism promotes lung tumor growth 25 samples shares il-9
- GSE173543 Altering metabolism to program cell identity via NAD+ dependent deacetylation 141 samples shares identity
- GSE330837 Active repression of muscle fate preserves neural lineage identity during cerebellum development 53 samples shares identity
- GSE243165 Signal-responsive transcription factors cooperate to establish alveolar macrophage identity 42 samples shares identity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.