Impact of Intestinal Propionate Metabolism on Systemic Metabolic Homeostasis
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE329264_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1458231 and SRA study SRP695378. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 5 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9700360 Chow, PCCA ff, replicate 1 Chow, PCCA ff,
- GSM9700361 Chow, PCCA ff, replicate 2 Chow, PCCA ff,
- GSM9700362 Chow, PCCA ff, replicate 3 Chow, PCCA ff,
- GSM9700363 Chow, PCCA ff, replicate 4 Chow, PCCA ff,
- GSM9700364 Chow, PCCA Vill, replicate 1 Chow, PCCA Vill,
- GSM9700365 Chow, PCCA Vill, replicate 2 Chow, PCCA Vill,
- GSM9700366 Chow, PCCA Vill, replicate 3 Chow, PCCA Vill,
- GSM9700367 Chow, PCCA Vill, replicate 4 Chow, PCCA Vill,
- GSM9700368 Chow, PCCA Alb, replicate 1 Chow, PCCA Alb,
- GSM9700369 Chow, PCCA Alb, replicate 2 Chow, PCCA Alb,
- GSM9700370 Chow, PCCA Alb, replicate 3 Chow, PCCA Alb,
- GSM9700371 Chow, PCCA Alb, replicate 4 Chow, PCCA Alb,
- GSM9700372 HFD, PCCA ff, replicate 1 HFD, PCCA ff,
- GSM9700373 HFD, PCCA ff, replicate 2 HFD, PCCA ff,
- GSM9700374 HFD, PCCA ff, replicate 3 HFD, PCCA ff,
- GSM9700375 HFD, PCCA ff, replicate 4 HFD, PCCA ff,
- GSM9700376 HFD, PCCA Vill, replicate 1 HFD, PCCA Vill,
- GSM9700377 HFD, PCCA Vill, replicate 2 HFD, PCCA Vill,
- GSM9700378 HFD, PCCA Vill, replicate 3 HFD, PCCA Vill,
- GSM9700379 HFD, PCCA Vill, replicate 4 HFD, PCCA Vill,
- GSE301459 Elucidating the impact of KRAS Gly12 mutants on homeostasis and tumorigenesis in the colonic epithelium 24 samples shares homeostasis, impact
- GSE307570 Localized FLASH Radiotherapy Reduces Long-Term Skin and Muscle Damage While Preserving Systemic Homeostasis 20 samples shares homeostasis, systemic
- GSE283571 Circadian reprogramming of protein homeostasis and glycolipid metabolism in diabetic nephropathy 47 samples shares homeostasis
- GSE326538 Aqueous Artemisia argyi extract mitigates acute lung injury by coordinating gut microbiota, metabolic homeostasis, and pulmonary inflammatory signaling 24 samples shares homeostasis
- GSE240578 MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis 20 samples shares homeostasis
- GSE237833 Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome 14 samples shares intestinal
- GSE238201 Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) [RNA-seq] 12 samples shares homeostasis
- GSE262065 A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery 10 samples shares intestinal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.