GEO series
IL-33 as a component of NETs mediates CIAKI by promoting ferroptosis in tubular epithelial cells
GSE337704
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/07/11
GPL24247
Summary
This study performed bulk RNA-seq on kidney tissues from WT contrast-induced acute kidney injury (CIAKI), PAD4 KO CIAKI, and IL33 KO CIAKI mice. The dataset was generated to investigate the roles of PAD4-dependent neutrophil extracellular traps (NETs) and IL-33 signaling in CIAKI. Transcriptomic comparisons were used to identify gene expression programs and pathways related to NETs activation, IL-33 signaling, and tubular injury.
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