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Transcriptomic profiling of liver tissues from DDC-treated and control mice

GSE337823 Mus musculus Expression profiling by high throughput sequencing 8 samples 2026/07/13 GPL24247
Summary
This study aimed to characterize transcriptomic alterations in mouse liver tissues during DDC-induced cholestatic liver injury and biliary fibrosis. Bulk RNA sequencing was performed on liver tissues from control and DDC-treated mice. Differential gene expression analysis was conducted to identify pathways associated with extracellular matrix remodeling, TGF-beta signaling and fibrosis.
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