GEO series
Hemin-induced DEGs in Lung, Kidney of WT and hepatic SR-BI KO mice
GSE338324
Mus musculus
Expression profiling by high throughput sequencing
18 samples
2026/07/15
GPL24247
Summary
Acute hemolysis can deplete haptoglobin and hemopexin, leaving toxic free heme insufficiently controlled. Here, the authors show that scavenger receptor BI (SR-BI) mediates hepatic uptake of free heme and is essential for protection against heme-induced injury and death. Here we examined gene expression post hemin injections
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