Cysteine and Glycine Rich Protein 3 (Csrp3) modulates cardiomyocyte mitotic cell cycle entry through Ring Finger Protein 5 (Rnf5)/p38 MAPK dependent pathway
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × WT P1 sample vs 3 × Csrp3 KO P1 sample vs 3 × WT P21 sample vs 3 × Csrp3 KO P21 sampleGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE342169_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1505726 and SRA study SRP723308. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9924428 WT P1 sample 1 WT P1 sample
- GSM9924429 WT P1 sample 2 WT P1 sample
- GSM9924430 WT P1 sample 3 WT P1 sample
- GSM9924431 Csrp3 KO P1 sample 1 Csrp3 KO P1 sample
- GSM9924432 Csrp3 KO P1 sample 2 Csrp3 KO P1 sample
- GSM9924433 Csrp3 KO P1 sample 3 Csrp3 KO P1 sample
- GSM9924434 WT P21 sample 1 WT P21 sample
- GSM9924435 WT P21 sample 2 WT P21 sample
- GSM9924436 WT P21 sample 3 WT P21 sample
- GSM9924437 Csrp3 KO P21 sample 1 Csrp3 KO P21 sample
- GSM9924438 Csrp3 KO P21 sample 2 Csrp3 KO P21 sample
- GSM9924439 Csrp3 KO P21 sample 3 Csrp3 KO P21 sample
- GSE277392 Kras loss of heterozygosity promotes MAPK dependent pancreatic ductal adenocarcinoma and induces therapeutic sensitivity 31 samples shares mapk, dependent
- GSE278577 β2 ADRENERGIC SIGNALING STIMULATES EARLY IL-1β SECRETION IN MACROPHAGES BY INDUCING MAPK-DEPENDENT Il1b TRANSCRIPTION [RNA-Seq] 30 samples shares mapk, dependent
- GSE280558 Junctional Epithelial Plakoglobin facilitates intestinal inflammation by p38MAPK-Dependent Activation of the Inflammasome 15 samples shares mapk, dependent
- GSE276325 Cardiomyocyte-specific knockout of ADAM17 alleviates doxorubicin-induced cardiomyopathy via inhibiting TNFα-TRAF3-TAK1-MAPK axis 12 samples shares mapk, cardiomyocyte
- GSE252607 Cardiomyocyte specific RXFP1-overexpression protects Relaxin-independently from pressure-overload induced cardiac dysfunction 30 samples shares cardiomyocyte, dependent
- GSE284354 Excitation-contraction coupling, cardiomyocyte electrophysiology, and transcriptome changes in two translational HFpEF murine models: Aetiology and sex-dependent differences 23 samples shares cardiomyocyte, dependent
- GSE336233 Cardiomyocyte-intrinsic somatic mtDNA mutations induce an OXPHOS-dependent immune response and promote progressive heart failure 17 samples shares cardiomyocyte, dependent
- GSE307773 Oncogenic MAPK signalling induces epithelial cell state change and therapeutic resistance in vivo [RNA-Seq] 175 samples shares mapk
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.