m6A mRNA Methylation Facilitates Resolution of Naïve Pluripotency Towards Differentiation (m6a-seq)
DNA methylation · mouse · 18 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 8 × IP vs 8 × InputGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI.
Read the full summary ↓
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE61995_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA262906 and SRA study SRP048596. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 2 replicated groups read from 18 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM1518024 m6A-seq in ESCs, replicate A: IP IP
- GSM1518025 m6A-seq in ESCs, replicate A: Input Input
- GSM1518026 m6A-seq in ESCs, replicate B: IP IP
- GSM1518027 m6A-seq in ESCs, replicate B: Input Input
- GSM1518028 m6A-seq in ESCs, replicate C: IP IP
- GSM1518029 m6A-seq in ESCs, replicate C: Input Input
- GSM1518030 m6A-seq in EBs, replicate A: IP IP
- GSM1518031 m6A-seq in EBs, replicate A: Input Input
- GSM1518032 m6A-seq in EBs, replicate B: IP IP
- GSM1518033 m6A-seq in EBs, replicate B: Input Input
- GSM1518034 m6A-seq in EBs, replicate C: IP IP
- GSM1518035 m6A-seq in EBs, replicate C: Input Input
- GSM1518036 m6A-seq in MEFs, replicate A: IP IP
- GSM1518037 m6A-seq in MEFs, replicate A: Input Input
- GSM1518038 m6A-seq in MEFs, replicate B: IP IP
- GSM1518039 m6A-seq in MEFs, replicate B: Input Input
- GSM1577791 m6A-seq in Mettl3-KO ESCs, IP
- GSM1577792 m6A-seq in Mettl3-KO ESCs, Input
- GSE242201 DNA methylation shapes the Polycomb landscape during the exit from naive pluripotency 39 samples shares pluripotency, methylation
- GSE100048 m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway 36 samples shares methylation, mrna
- GSE293593 Slow RNAPII elongation facilitates early pluripotency cell transitions without reducing replication fork rates 17 samples shares pluripotency, facilitates
- GSE242461 TET Proteins Control Early-Stage Stem Cell Differentiation via H3K27me3, Not DNA Demethylation 30 samples shares methylation
- GSE166226 Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates 615 samples shares methylation
- GSE222746 Enhanced activities of OCT4 and SOX2 facilitates epigenetic reprogramming by modulating cell cycle 460 samples shares facilitates
- GSE222745 Enhanced activities of OCT4 and SOX2 facilitates epigenetic reprogramming by modulating cell cycle [scRNA-Seq] 422 samples shares facilitates
- GSE166225 Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates [RNA-seq] 288 samples shares methylation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.