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Whole genome DNAse hypersensitivity in human CD4+ T-cells

GSE8486 Homo sapiens (human) ChIP-seq / ATAC-seq (genome binding and open chromatin) 78 samples Submitted 2007/11/19 Platform GPL5591Platform GPL5554Platform GPL5594Platform GPL5597Platform GPL5551Platform GPL5614Platform GPL5534Platform GPL5583Platform GPL5537Platform GPL5540Platform GPL5557Platform GPL5603Platform GPL5560Platform GPL5600Platform GPL5580Platform GPL5543Platform GPL5563Platform GPL5546Platform GPL5549Platform GPL5592Platform GPL5586Platform GPL5566Platform GPL5612Platform GPL5606Platform GPL5569Platform GPL5609Platform GPL5589Platform GPL5555Platform GPL5558Platform GPL5595Platform GPL5538Platform GPL5615Platform GPL5598Platform GPL5535Platform GPL5552Platform GPL5601Platform GPL5564Platform GPL5604Platform GPL6314Platform GPL5607Platform GPL5584Platform GPL5587Platform GPL5541Platform GPL5581Platform GPL5561Platform GPL5593Platform GPL5610Platform GPL5544Platform GPL5547Platform GPL5613Platform GPL5567Platform GPL5533Platform GPL5616Platform GPL5553Platform GPL5570Platform GPL5556Platform GPL5550Platform GPL5590Platform GPL6300Platform GPL5582Platform GPL5602Platform GPL5536Platform GPL5539Platform GPL5559Platform GPL5579Platform GPL5596Platform GPL5599Platform GPL5565Platform GPL5611Platform GPL5545Platform GPL5585Platform GPL5548Platform GPL5588Platform GPL5542Platform GPL5568Platform GPL5562Platform GPL5605Platform GPL5608
At a glance

ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 78 samples

What it is
ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
Organism
Homo sapiens (human)
Samples
78 samples
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Summary (written by the submitters)
Mapping DNaseI hypersensitive (HS) sites is an accurate method of identifying the location of genetic regulatory elements, including promoters, enhancers, silencers, insulators, and locus control regions. We employed whole genome tiled array strategies to identify DNaseI HS sites within human primary CD4+ T cells. Keywords: whole genome tiling array
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE8486_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.

Also filed as BioProject PRJNA101577. Searching any of these in the dataset finder brings you back here.

Samples in this study

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+ 78 more — browse all 78 samples with per-sample file links →

Datasets on a similar topic

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