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Gene profile data from Df(16)A/+ and wild type littermates

GSE10784 Mus musculus Expression profiling by array 40 samples Submitted 2008/04/10 Platform GPL1261
Summary
This represents an unbiased evaluation of the transcriptional response in the prefrontal cortex and hippocampus areas in the Df(16)A/+ mice, a mouse model of human 22q11 microdeletion syndrome. These mice were generated by chromosomal engineering and carry a microdeltion of ~1.3Mb in the mouse locus syntenic to the human 22q11.1 The reasoning behind this expression profiling is that alterations in transcriptional programs reflect either downstream (immediate or remote) effects of the deficiency or reactive (compensatory) changes, and can thus point to affected biological processes and molecular functions. Keywords: disease state analysis, genetic modification
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Also filed as BioProject PRJNA107471. Searching any of these in the dataset finder brings you back here.

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