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Adipocyte thyroid hormone receptor β determines the intracellular usage and fate of glucose and governs systemic homeostasis

GSE205520 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2025/06/06 Platform GPL24247
Summary
To investigate the effect of thyroid hormone and its receptor on glucose and lipid metabolism in white adipose tissue (WAT), and the effect of thyroid hormone and its receptor on WAT regulation on glucose metabolism and obesity. We constructed mice with adipose tissue-specific knockout of thyroid hormone receptor beta(ATRβKO mice). ATRβKO mice were given T3 stimulation or high-fat feeding. We then performed gene expression profiling analysis using data obtained from RNA-seq of White adipose tissue from knockout ATRβKO mice treated with T3 or HFD feeding.
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Also filed as BioProject PRJNA846197 and SRA study SRP378591. Searching any of these in the dataset finder brings you back here.

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