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Analysis of lncRNA-mRNA co-expression profiles in CD133 positive cancer stem-like cells from osteosarcoma cell line Saos-2

GSE207333 Homo sapiens (human) Non-coding RNA profiling 12 samples Submitted 2024/06/01 Platform GPL24676
At a glance

Non-coding RNA profiling · human · 12 samples

What it is
Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
Organism
Homo sapiens (human)
Topic
OsteosarcomaThis series is part of our curated briefing on it.
Samples
12 samples
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Summary (written by the submitters)
Osteosarcoma (OS) is an essential threatening tumor of bone in young adults. OS stem cells (OSCs) act a significant role in the occurrence, metastasis, drug resistance and recurrence of OS. CD133 is an integral membrane glycoprotein, which has been identified as an OSCs marker. However, the mechanisms of metastasis, chemoresistance and progression in CD133(+) OSCs need to be further explored. We aim to detect the lncRNA and mRNA profiles in CD133(+) cells compared with CD133(-) cells from the Saos-2 cell line in the present study.
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE207333_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Also filed as BioProject PRJNA854881 and SRA study SRP384519. Searching any of these in the dataset finder brings you back here.

Samples in this study

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