The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia (CLL)
Expression microarray · human · 62 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Topic
- Chronic lymphocytic leukemiaThis series is part of our curated briefing on it.
- Samples
- 62 samples
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE21029_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA126449. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 62 more — browse all 62 samples with per-sample file links →
- GSE270461 Adipose-derived Stem cll and Stronal Vascular Fraction response to inflammation sc RNA seq 4 samples same disease briefing · shares cll, nf
- GSE313098 Time-series RNA-seq analysis reveals dynamic transcriptional responses and crosstalk in chronic lymphocytic leukaemia (CLL) autologous and monoculture in vitro models 60 samples same disease briefing · shares cll, lymphocytic
- GSE305855 Casein kinase 1δ/ε inhibition suppresses CLL through cell-intrinsic and microenvironmental mechanisms [RNA-Seq] 42 samples same disease briefing · shares cll, microenvironment
- GSE283045 PD-1 expression identifies activated and proliferating chronic lymphocytic leukemia cells and is a potential biomarker that informs response and resistance to BTK inhibitor therapy 35 samples same disease briefing · shares nf, lymphocytic
- GSE329311 B cell receptor-mediated amplification of the interferon response in CLL cells 12 samples same disease briefing · shares cll, receptor
- GSE261569 POT1 mutations identify inferior outcomes in chronic lymphocytic leukemia and disrupted telomere biology function 6 samples same disease briefing · shares nf, lymphocytic
- GSE292026 2p Gain-Driven REL Overexpression Confers Resistance to BTK Inhibitors in Chronic Lymphocytic Leukemia 5 samples same disease briefing · shares nf, lymphocytic
- GSE264554 CD40 stimulation + dasatinib treatment of chronic lymphocytic leukemia (CLL) cells 3 samples same disease briefing · shares cll, lymphocytic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.