Genome-wide gene expression profiling on pre-chemotherapy biopsies of osteosarcoma patients who developed metastases within 5yrs (n=34) and patients who did not develop metastases within 5yrs (n=19)
Expression microarray · human · 53 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Topic
- OsteosarcomaThis series is part of our curated briefing on it.
- Samples
- 53 samples
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE21257_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA126279. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 53 more — browse all 53 samples with per-sample file links →
- GSE42352 Genome-wide gene expression profiling of mesenchymal stem cells, osteosarcoma cells, and osteosarcoma cell lines. 118 samples same disease briefing · shares osteosarcoma, genome-wide
- GSE19276 Osteosarcoma is characterized by impaired osteoclastogenesis and antigen presentation compared to normal bone 49 samples same disease briefing · shares osteosarcoma
- GSE270506 Epigenetic heterogeneity and state-specific transcriptional programs determine differential drug response in osteosarcoma. 279 samples same disease briefing · shares osteosarcoma
- GSE259286 In vitro modeling of nutritional and mitochondrial-targeted therapies for osteosarcoma 98 samples same disease briefing · shares osteosarcoma
- GSE253548 The whole transcriptome analysis using FFPE and fresh tissue samples identifies the molecular fingerprint of osteosarcoma 90 samples same disease briefing · shares osteosarcoma
- GSE270502 Epigenetic heterogeneity and state-specific transcriptional programs determine differential drug response in osteosarcoma [ATAC-seq] 87 samples same disease briefing · shares osteosarcoma
- GSE309031 Epigenetic heterogeneity and state-specific transcriptional programs determine differential drug response in osteosarcoma [CUT&Run] 85 samples same disease briefing · shares osteosarcoma
- GSE152048 Single cell analysis of osteosarcoma tissues 76 samples same disease briefing · shares osteosarcoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.