Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 120 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 120 samples: 7 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Targeting immune-fibroblast cell communication in heart failureNature · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE218392_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA903478 and SRA study SRP516372. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 96 samples.
How we read this: 7 replicated groups read from 120 sample titles; they account for 96 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6720563 GEX_sample1 GEX_sample
- GSM6720564 GEX_sample2 GEX_sample
- GSM6720565 GEX_sample4 GEX_sample
- GSM6720566 GEX_sample5 GEX_sample
- GSM6720567 GEX_sample6 GEX_sample
- GSM6720568 GEX_sample7 GEX_sample
- GSM6720569 GEX_sample8 GEX_sample
- GSM6720570 GEX_sample9 GEX_sample
- GSM6720571 GEX_sample12 GEX_sample
- GSM6720572 GEX_sample13 GEX_sample
- GSM6720573 GEX_sample15 GEX_sample
- GSM6720574 GEX_sample17 GEX_sample
- GSM6720575 GEX_sample27 GEX_sample
- GSM6720576 GEX_sample28 GEX_sample
- GSM6720577 GEX_sample29 GEX_sample
- GSM6720578 GEX_sample30 GEX_sample
- GSM6720579 GEX_sample32 GEX_sample
- GSM6720580 GEX_sample33 GEX_sample
- GSM6720581 GEX_sample34 GEX_sample
- GSM6720582 GEX_sample39 GEX_sample
- GSM6720583 GEX_sample41 GEX_sample
- GSM6720584 GEX_sample42 GEX_sample
- GSM6720585 Ab_sample1 Ab_sample
- GSM6720586 Ab_sample2 Ab_sample
- GSM6720587 Ab_sample4 Ab_sample
- GSM6720588 Ab_sample5 Ab_sample
- GSM6720589 Ab_sample6 Ab_sample
- GSM6720590 Ab_sample7 Ab_sample
- GSM6720591 Ab_sample8 Ab_sample
- GSM6720592 Ab_sample9 Ab_sample
- GSM6720593 Ab_sample12 Ab_sample
- GSM6720594 Ab_sample13 Ab_sample
- GSM6720595 Ab_sample15 Ab_sample
- GSM6720596 Ab_sample17 Ab_sample
- GSM6720597 Ab_sample27 Ab_sample
- GSM6720598 Ab_sample28 Ab_sample
- GSM6720599 Ab_sample29 Ab_sample
- GSM6720600 Ab_sample30 Ab_sample
- GSM6720601 Ab_sample32 Ab_sample
- GSM6720602 Ab_sample33 Ab_sample
+ 80 more — browse all 120 samples with per-sample file links →
- GSE261554 Targeting Vdac2 overcomes immunotherapy resistance by inducing tumor cell death and inflammation 180 samples shares targeting
- GSE52947 Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 118 samples shares targeting
- GSE279644 BCR::ABL1-induced enhancer reprogramming uncovers hypersensitivity of Ph+B-ALL cells to enhancer-targeting drugs [ChIP-Seq] 91 samples shares targeting
- GSE266135 Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma 90 samples shares targeting
- GSE271447 Myocardial Reprogramming by HMGN1 Underlies Heart Defects in Trisomy 21 84 samples shares myocardial
- GSE280643 Differential KEAP1/NRF2-mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy 74 samples shares targeting
- GSE266391 Suppressing Aberrant Hedgehog Pathway and Overcoming Resistance to Smoothened Antagonists via Targeting Super-enhancer-driven Transcriptional Dependencies 74 samples shares targeting
- GSE282436 Development of a potent epigenetic editor targeting human PCSK9 with durable reduction of cholesterol in mice and non-human primates [hybrid capture methylseq] 66 samples shares targeting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.