Eosinophils Restrain Humoral Alloimmunity after Lung Transplantation
RNA-seq (gene expression) · mouse · 19 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples: 5 × Resting_Lung vs 5 × Day 7 vs 5 × Day 30Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Eosinophils restrain humoral alloimmunity after lung transplantationJCI insight · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE223907_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA928784 and SRA study SRP418326. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 3 replicated groups read from 19 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6944101 zmlx175_Eosinophil deficient
- GSM6944102 zmlx176_Eosinophil deficient
- GSM6944103 zmlx180_Eosinophil deficient
- GSM6944104 zmlx181_Eosinophil deficient
- GSM6946010 Resting_Lung 1 Resting_Lung
- GSM6946011 Resting_Lung 2 Resting_Lung
- GSM6946012 Resting_Lung 3 Resting_Lung
- GSM6946013 Resting_Lung 4 Resting_Lung
- GSM6946014 Resting_Lung 5 Resting_Lung
- GSM6946015 Day 7_1 Day 7
- GSM6946016 Day 7_2 Day 7
- GSM6946017 Day 7_3 Day 7
- GSM6946018 Day 7_4 Day 7
- GSM6946019 Day 7_5 Day 7
- GSM6946020 Day 30_1 Day 30
- GSM6946021 Day 30_2 Day 30
- GSM6946022 Day 30_3 Day 30
- GSM6946023 Day 30_4 Day 30
- GSM6946024 Day 30_5 Day 30
- GSE286908 Bacterial skin infection imprints bone marrow eosinophils to promote allergic skin-lung crosstalk [Quant_seq] 24 samples shares eosinophils, lung
- GSE223352 Eosinophils in Lung Allograft 20 samples shares eosinophils, lung
- GSE334205 Sympathetic Neurons Restrain Pancreatic Cancer Lung Metastatic seeding through NPY-NPY1R Signaling [scRNA-seq] 16 samples shares restrain, lung
- GSE259429 Antibiotic use during influenza infection augments lung eosinophils that impair lung immunity against secondary bacterial pneumonia 12 samples shares eosinophils, lung
- GSE276158 Ischemia reperfusion injury (IRI) following syngeneic lung transplantation 11 samples shares transplantation, lung
- GSE251931 Maintenance of tolerance after lung transplantation is dependent on the preservation of allograft tissue-resident Foxp3+ T cells 15 samples shares transplantation, lung
- GSE165881 Establishment of hematopoietic stem cell compartment after single cell transplantation tracked by FIT approach 62 samples shares transplantation
- GSE301699 A population of Regulatory T cells controls nociception through enkephalins to restrain skin inflammation. 386 samples shares restrain
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.