Co-option of CENP-A for activity-induced neuronal plasticity
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 8 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 8 samples: 3 × Hippocampi, Saline, vs 3 × Hippocampi, PTZ,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230784_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA962563 and SRA study SRP434914. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 2 replicated groups read from 8 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9531884 Hippocampi, Saline, rep 1 Hippocampi, Saline,
- GSM9531885 Hippocampi, Saline, rep 2 Hippocampi, Saline,
- GSM9531886 Hippocampi, Saline, rep 3 Hippocampi, Saline,
- GSM9531887 Hippocampi, PTZ, rep 1 Hippocampi, PTZ,
- GSM9531888 Hippocampi, PTZ, rep 2 Hippocampi, PTZ,
- GSM9531889 Hippocampi, PTZ, rep 3 Hippocampi, PTZ,
- GSM9531890 input Hippocampi, Saline, rep 1
- GSM9531891 input Hippocampi, PTZ, rep 1
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples shares plasticity, neuronal
- GSE306265 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity 106 samples shares plasticity, neuronal
- GSE249978 Egr1 is a sex-specific regulator of neuronal chromatin, synaptic plasticity, and behaviour 52 samples shares plasticity, neuronal
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares plasticity, neuronal
- GSE276528 Molecular states underlying neuronal cell type development and plasticity in the whisker cortex 12 samples shares plasticity, neuronal
- GSE278571 Neuron-targeted caveolin-1 enhances the neuroprotective, neuronal and synaptic plasticity transcriptome and improves cognitive function in symptomatic Alzheimer’s Disease models 10 samples shares plasticity, neuronal
- GSE327851 Transneuronal cytokine delivery promotes functional recovery across spinal cord contusion severities via descending circuit plasticity 9 samples shares plasticity, neuronal
- GSE266175 Plasticity and lineage commitment of individual Th1 cells are determined by stable T-bet expression quantities (ChIP-Seq) 84 samples shares plasticity
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.