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Gene expression and chromatin accessibility profile at single cell level of B16 cells [B16_D0_3_5_scMulti]

GSE233134 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2024/07/05 Platform GPL30172
Summary
B16 F10 is a depigmented mouse melanoma cell line which is considered as a homogeneous cell population. These cells when cultured at a very low density of 100 cells/cm2 starts to pigment progressively. We used single nucleus RNA+ATAC sequencing (scMultiomics) to analyze the transciptional diversity and to investigate the epigenetic basis of this diversity of day 0, 3 and 5 B16 cells cultured at low density.
Published in
Distinct melanocyte subpopulations defined by stochastic expression of proliferation or maturation programs enable a rapid and sustainable pigmentation response
Aggarwal A, Nasreen A, Sharma B et al. · PLoS biology 2024 · PMID 39163475 · doi:10.1371/journal.pbio.3002776
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Direct links to NCBI, no account and no request form: the whole study as GSE233134_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA975102 and SRA study SRP438946. Searching any of these in the dataset finder brings you back here.

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