GEO series
Determining the chromatin accessibility profiles of functionally distinct SHH-medulloblastoma sub-populations
GSE233993
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2024/09/11
GPL17021
Summary
Using FACS sorting on SOX2-eGFP and MKi67-RFP mice on a Ptch1+/- background, we identified cycling& non-cycling stem cells and tumor bulk subpopulations in endpoint mouse SHH-subgroup medulloblastoma tumors, and determined their chromatin accessibility progiles to identify unique regulators of cell state.
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Paper (PMID 39904987) ↗
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