Sex specific role of KDM5B demethylase in Alcohol-associated Liver Disease development and resolution
RNA-seq (gene expression) · mouse · 27 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 27 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244240_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1021978 and SRA study SRP463672. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 27 more — browse all 27 samples with per-sample file links →
- GSE311802 Autism-like phenotypes and increased NMDAR2D expression in mice with KDM5B histone lysine demethylase deficiency 16 samples shares kdm5b, demethylase
- GSE288043 Characterization of ALDH2-deficient alcohol-associated liver disease (duodenum RNA seq) 25 samples shares alcohol-associated, liver
- GSE244388 PCB126 Modifies the Murine Hepatic Transcriptome and Metallome to Promote Alcohol-associated Liver Disease Pathogenesis 24 samples shares alcohol-associated, liver
- GSE288842 Perfluorooctane sulfonate (PFOS) exposure and alcohol-associated liver disease severity in a mouse chronic-binge ethanol feeding model 24 samples shares alcohol-associated, liver
- GSE328655 A high-resolution, sex-stratified atlas of transcriptional and alternative splicing dynamics in the fasting mouse liver. 80 samples shares resolution, liver
- GSE223882 Thyroid hormone receptor beta1 action in the resolution of liver fibrosis 32 samples shares resolution, liver
- GSE261310 Modulation of liver cholesterol homeostasis by choline supplementation during fibrosis resolution 16 samples shares resolution, liver
- GSE317551 Aldehyde dehydrogenase 2 deficiency exacerbates alcohol-associated liver fibrosis 15 samples shares alcohol-associated, liver
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.