Short-term cold exposure induces persistent epigenomic memory in brown fat [RNA-Seq]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Short-term cold exposure induces persistent epigenomic memory in brown fatCell metabolism · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244385_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1022504 and SRA study SRP463980. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7814547 Control_22C_rep1 Control_22C
- GSM7814548 Control_22C_rep2 Control_22C
- GSM7814549 Control_22C_rep3 Control_22C
- GSM7814550 Control_22C_rep4 Control_22C
- GSM7814551 KO_22C_rep1 KO_22C
- GSM7814552 KO_22C_rep2 KO_22C
- GSM7814553 KO_22C_rep3 KO_22C
- GSM7814554 KO_22C_rep4 KO_22C
- GSM7814555 Control_24h_Rec_rep1 Control_24h_Rec
- GSM7814556 Control_24h_Rec_rep2 Control_24h_Rec
- GSM7814557 Control_24h_Rec_rep3 Control_24h_Rec
- GSM7814558 Control_24h_Rec_rep4 Control_24h_Rec
- GSM7814559 KO_24h_Rec_rep1 KO_24h_Rec
- GSM7814560 KO_24h_Rec_rep2 KO_24h_Rec
- GSM7814561 KO_24h_Rec_rep3 KO_24h_Rec
- GSM7814562 KO_24h_Rec_rep4 KO_24h_Rec
- GSM7814563 Control_7d_Rec_rep1 Control_7d_Rec
- GSM7814564 Control_7d_Rec_rep2 Control_7d_Rec
- GSM7814565 Control_7d_Rec_rep3 Control_7d_Rec
- GSM7814566 Control_7d_Rec_rep4 Control_7d_Rec
- GSM7814567 KO_7d_Rec_rep1 KO_7d_Rec
- GSM7814568 KO_7d_Rec_rep2 KO_7d_Rec
- GSM7814569 KO_7d_Rec_rep3 KO_7d_Rec
- GSM7814570 KO_7d_Rec_rep4 KO_7d_Rec
- GSE325692 Multi-omic analysis reveals brain-blood concordance and persistent neuroimmune reprogramming with stress and toxicant exposure in a mouse model of Gulf War Illness [RNA-Seq] 30 samples shares persistent, exposure, rna-seq
- GSE286904 Persistent large-scale changes in alternative splicing in prefrontal cortical neuron types following psychedelic exposure 118 samples shares persistent, exposure
- GSE302857 Multi-tier signaling and epigenomic reprogramming drive microglial inflammatory states and functions associated with demyelination [RNA-seq] 81 samples shares epigenomic, rna-seq
- GSE272929 Transcriptomic and Epigenomic Signatures Distinguish High- and Low-Risk Endotypes for Liver Tumor Development [RNA-Seq liver] 75 samples shares epigenomic, rna-seq
- GSE330728 Single-nucleus RNA-seq atlas of 17 ASD-risk mouse lines under early-postnatal fluoxetine or lithium exposure (4-plex On-Chip Multiplexed) 53 samples shares exposure, rna-seq
- GSE279536 Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs [RNA-seq] 38 samples shares epigenomic, rna-seq
- GSE298802 The TBLR1/TBL1 co-factor complex acts as a transcriptional checkpoint in the brown adipose tissue response to prolonged cold exposure 24 samples shares exposure, brown
- GSE226609 Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure. 20 samples shares exposure, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.