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EDA2R signaling drives cancer-associated skeletal muscle wasting [bulkRNA-Seq]

GSE245799 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/07/13 Platform GPL24247
Summary
We investigated the impact of EDA-A2-EDA2R signaling in gene expression profiles of mouse primary myotubes. Cells were treated with recombinant EDA-A2 for 24hrs and transcriptional changes were studied by RNA-sequencing.
Published in
Tumour-induced alterations in single-nucleus transcriptome of atrophying muscles indicate enhanced protein degradation and reduced oxidative metabolism
Agca S, Domaniku-Waraich A, Bilgic SN et al. · Journal of cachexia, sarcopenia and muscle 2024 · PMID 39001644 · doi:10.1002/jcsm.13540
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Also filed as BioProject PRJNA1029991 and SRA study SRP467362. Searching any of these in the dataset finder brings you back here.

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