GEO series
Double Negative T Cells Downregulate Intrahepatic Inflammation and Ameliorate Hepatic Ischemia and Reperfusion Injury via CD39-adenosinergic axis [RNA-seq]
GSE246300
Mus musculus
Expression profiling by high throughput sequencing
18 samples
2025/01/29
GPL24247
Summary
Converted double negative T cells (cDNT) highly express CD39 and hydrolyze ATP into adenosine. ATP/adenosine derived purinergic signaling plays a critical role in immune regulation. However, the role and mechanisms of ATP/adenosine in cDNT is unclear.
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Paper (PMID 39658411) ↗
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