Cell cycle checkpoint proficiency of endometrial cancer cells
RNA-seq (gene expression) · human · 42 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Endometrial cancerThis series is part of our curated briefing on it.
- Samples
- 42 samples: 41 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial CarcinomaCancer research communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE247793_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1040325 and SRA study SRP471911. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 42 sample titles: 41 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7900807 ARK1 Abema replicate 1 (batch 1)
- GSM7900808 ARK1 Abema replicate 2 (batch 1)
- GSM7900809 ARK1 DMSO control replicate 1 (batch 1)
- GSM7900810 ARK1 DMSO control replicate 2 (batch 1)
- GSM7900811 HEC1B Abema replicate 1 (batch 1)
- GSM7900812 HEC1B Abema replicate 2 (batch 1)
- GSM7900813 HEC1B DMSO control replicate 1 (batch 1)
- GSM7900814 HEC1B DMSO control replicate 2 (batch 1)
- GSM7900815 EMCA-A DMSO control replicate 2 (batch 2)
- GSM7900816 EMCA-A DMSO control replicate 1 (batch 2)
- GSM7900817 EMCA-A Abema replicate 2 (batch 2)
- GSM7900818 EMCA-A Abema replicate 1 (batch 2)
- GSM7900823 CS-A DMSO control replicate 2 (batch 2)
- GSM7900824 CS-A DMSO control replicate 1 (batch 2)
- GSM7900825 CS-A Abema replicate 2 (batch 2)
- GSM7900826 CS-A Abema replicate 1 (batch 2)
- GSM7900827 UPSC-A DMSO control replicate 2 (batch 2)
- GSM7900828 UPSC-A DMSO control replicate 1 (batch 2)
- GSM7900829 UPSC-A Abema replicate 2 (batch 2)
- GSM7900830 UPSC-A Abema replicate 1 (batch 2)
- GSM7900833 UPSC-A DMSO control replicate 3 (batch 3)
- GSM7900834 UPSC-A DMSO control replicate 4 (batch 3)
- GSM7900837 CS-A DMSO control replicate 3 (batch 3)
- GSM7900838 CS-A DMSO control replicate 4 (batch 3)
- GSM7900845 EMCA-A DMSO control replicate 3 (batch 3)
- GSM7900846 EMCA-A DMSO control replicate 4 (batch 3)
- GSM7900849 CS-B DMSO control replicate 1 (batch 3)
- GSM7900850 CS-B DMSO control replicate 2 (batch 3)
- GSM7900853 AN3CA DMSO control replicate 1 (batch 3)
- GSM7900854 AN3CA DMSO control replicate 2 (batch 3)
- GSM7900857 ARK1 DMSO control replicate 3 (batch 3)
- GSM7900858 ARK1 DMSO control replicate 4 (batch 3)
- GSM7900861 HEC1B DMSO control replicate 3 (batch 3)
- GSM7900862 HEC1B DMSO control replicate 4 (batch 3)
- GSM7900865 KLE DMSO control replicate 1 (batch 3)
- GSM7900866 KLE DMSO control replicate 2 (batch 3)
- GSM7900867 ARK1
- GSM7900868 ARK2
- GSM7900869 CS-A
- GSM7900870 UPSC-A
+ 2 more — browse all 42 samples with per-sample file links →
- GSE319248 Histone Demethylase KDM4A Activates ERRγ-Dependent Cell Cycle Progression to Promote Endometrial Cancer Progression 4 samples same disease briefing · shares endometrial, cycle
- GSE268903 Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study 10 samples same disease briefing · shares endometrial, checkpoint
- GSE307568 Patient-derived organoid – immune cell co-culture platform for therapeutics discovery in high-grade endometrial cancer 189 samples same disease briefing · shares endometrial
- GSE298672 Altered gene expression by C1orf106 in endometrial cancer cells. 6 samples same disease briefing · shares endometrial
- GSE310724 Loss of CSDE1 Function Enhances mRNA Stability of Interleukin-6 and Promotes Malignant Transformation in Endometrial Cancer Cells. 6 samples same disease briefing · shares endometrial
- GSE272263 Adipocyte induced distinct gene expression profiling of human endometrioid endometrial cancer cells upon SIRT1 inhibition. 5 samples same disease briefing · shares endometrial
- GSE17025 Gene Expression Analysis of Stage I Endometrial Cancers 103 samples same disease briefing · shares endometrial
- GSE323968 Transcriptional signatures indicating RB function may predict response to CDK4/6 inhibition in endometrial cancer 56 samples same disease briefing · shares endometrial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.