The gene expression of HUVEC in response to the cytokine stimulations
RNA-seq (gene expression) · human · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 15 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1Cell reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE254958_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1072704 and SRA study SRP487790. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 15 samples.
How we read this: 5 replicated groups read from 15 sample titles; they account for 15 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8061353 HUVEC, control1 HUVEC, control
- GSM8061354 HUVEC, control2 HUVEC, control
- GSM8061355 HUVEC, control3 HUVEC, control
- GSM8061356 HUVEC, TNFa1 HUVEC, TNFa
- GSM8061357 HUVEC, TNFa2 HUVEC, TNFa
- GSM8061358 HUVEC, TNFa3 HUVEC, TNFa
- GSM8061359 HUVEC,LTa1b2-1 HUVEC,LTa1b2
- GSM8061360 HUVEC,LTa1b2-2 HUVEC,LTa1b2
- GSM8061361 HUVEC,LTa1b2-3 HUVEC,LTa1b2
- GSM8061362 HUVEC, IL4-1 HUVEC, IL4
- GSM8061363 HUVEC, IL4-2 HUVEC, IL4
- GSM8061364 HUVEC, IL4-3 HUVEC, IL4
- GSM8061365 HUVEC, IFNg-1 HUVEC, IFNg
- GSM8061366 HUVEC, IFNg-2 HUVEC, IFNg
- GSM8061367 HUVEC, IFNg-3 HUVEC, IFNg
- GSE260954 Effect of iPSC-derived megakaryocytes and platelets on gene expression of HUVEC 12 samples shares huvec
- GSE288064 RNA sequencing of HUVEC, HCMEC and human primary skeletal muscle cells in response to in vitro mechanical loading 36 samples shares huvec
- GSE241023 Investigation of differentially expressed genes in subpopulations of adherent human umbilical vein endothelial cells (HUVECS) isolated after fluid shear stress compared to the whole population of endothelial cells 12 samples shares huvec
- GSE279106 Transcriptome analysis of HUVECs and those transduced with hiHepPC-inducing factors in culture with or without CHIR99021 [RNA-Seq] 25 samples shares huvec
- GSE296345 Paired-end RNA Sequencing on primary human umbilical endothelial cells (HUVEC) exposed to uninfected or bacterially-infected PMA-differentiated macrophage-like U937 for 8 or 24 h 24 samples shares huvec
- GSE278916 RNA sequencing in untreated (UN), sodium arsenite (SA) and heat shock (HS) stressed HeLa,HUVEC and THP-1 cells 18 samples shares huvec
- GSE275227 Transcriptomic changes in Human Umbilical Vein Endothelial Cells (HUVEC) after exposure to Tumor Necrosis Factor-Alpha(TNF-a), AdipoRon, and Sphingosine Kinase Inhibitor (SKI-I) 12 samples shares huvec
- GSE298356 Endothelins positively influences the proliferation vs migration balance of IDH1-mutant glioma cells and promotes proneural to mesenchymal transition [RNAseq-275HUVEC] 12 samples shares huvec
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.