Expression changes after loss of Dot1l in murine MLL-AF9 leukemia cells
Expression microarray · mouse · 26 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 6 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE25911_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA135857. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 6 replicated groups read from 26 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM636698 Cre_day_3-1 Cre_day_3
- GSM636699 Cre_day_3-2 Cre_day_3
- GSM636700 Cre_day_3-3 Cre_day_3
- GSM636701 Cre_day_3-4 Cre_day_3
- GSM636702 Cre_day_3-5 Cre_day_3
- GSM636703 MIY_day_3-1 MIY_day_3
- GSM636704 MIY_day_3-2 MIY_day_3
- GSM636705 MIY_day_3-3 MIY_day_3
- GSM636706 MIY_day_3-4 MIY_day_3
- GSM636707 Cre_day_5-1 Cre_day_5
- GSM636708 Cre_day_5-2 Cre_day_5
- GSM636709 Cre_day_5-3 Cre_day_5
- GSM636710 Cre_day_5-4 Cre_day_5
- GSM636711 Cre_day_5-5 Cre_day_5
- GSM636712 MIY_day_5-1 MIY_day_5
- GSM636713 MIY_day_5-2 MIY_day_5
- GSM636714 MIY_day_5-3 MIY_day_5
- GSM636715 MIY_day_5-4 MIY_day_5
- GSM636716 MIY_day_5-5 MIY_day_5
- GSM636717 Cre_day_7-1 Cre_day_7
- GSM636718 Cre_day_7-2 Cre_day_7
- GSM636719 Cre_day_7-3 Cre_day_7
- GSM636720 MIY_day_7-1 MIY_day_7
- GSM636721 MIY_day_7-2 MIY_day_7
- GSM636722 MIY_day_7-3 MIY_day_7
- GSM636723 MIY_day_7-4 MIY_day_7
- GSE313096 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators 40 samples shares leukemia, changes
- GSE280195 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators [ChIP-seq] 25 samples shares leukemia, changes
- GSE225843 Hepatic transcriptomic changes following equivalent weight loss by calorie restriction or vertical sleeve gastrectomy in mice with hepatic steatosis 12 samples shares changes, loss
- GSE266580 Ablation of Id1 Reduces Clonal Hematopoiesis, Genomic Instability and Delays Leukemia in Mice with Tet2 Loss of Function [RNA-seq] 12 samples shares leukemia, loss
- GSE233975 DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID 45 samples shares dot1l
- GSE290944 DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID. [ChIP-seq] 24 samples shares dot1l
- GSE306634 DOT1L-mediated H3K79me2 directs B-cell repertoire establishment, marginal zone development and germinal center function 21 samples shares dot1l
- GSE292609 ChIP-seq analysis of control and DOT1L HET cortical nuclei. 18 samples shares dot1l
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.