Low-dose exposure to microplastics retards meiotic maturation via HDACs insufficiency
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE259264_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1080548 and SRA study SRP491784. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 12 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8112459 H4K16ac-con 1 H4K16ac-con
- GSM8112460 H4K16ac-con 2 H4K16ac-con
- GSM8112461 H4K16ac-in vivo PSMPs 1 H4K16ac-in vivo PSMPs
- GSM8112462 H4K16ac-in vivo PSMPs 2 H4K16ac-in vivo PSMPs
- GSM8112463 H4K16ac-in vitro PSMPs 1 H4K16ac-in vitro PSMPs
- GSM8112464 H4K16ac-in vitro PSMPs 2 H4K16ac-in vitro PSMPs
- GSM8112465 H4K16ac-SAHA 1 H4K16ac-SAHA
- GSM8112466 H4K16ac-SAHA 2 H4K16ac-SAHA
- GSM8112467 H4K16ac-PSMPs & OE-Hdac3 1 H4K16ac-PSMPs & OE-Hdac3
- GSM8112468 H4K16ac-PSMPs & OE-Hdac3 2 H4K16ac-PSMPs & OE-Hdac3
- GSM8112469 H4K16ac-con-invitro 1 H4K16ac-con-invitro
- GSM8112470 H4K16ac-con-invitro 2 H4K16ac-con-invitro
- GSM8112471 RNA-con 1 RNA-con
- GSM8112472 RNA-con 2 RNA-con
- GSM8112473 RNA-in vivo PSMPs 1 RNA-in vivo PSMPs
- GSM8112474 RNA-in vivo PSMPs 2 RNA-in vivo PSMPs
- GSM8112475 RNA-in vitro PSMPs 1 RNA-in vitro PSMPs
- GSM8112476 RNA-in vitro PSMPs 2 RNA-in vitro PSMPs
- GSM8112477 RNA-SAHA 1 RNA-SAHA
- GSM8112478 RNA-SAHA 2 RNA-SAHA
- GSM8112479 RNA-PSMPs & OE-Hdac3 1 RNA-PSMPs & OE-Hdac3
- GSM8112480 RNA-PSMPs & OE-Hdac3 2 RNA-PSMPs & OE-Hdac3
- GSM8112481 RNA-con-in vitro 1 RNA-con-in vitro
- GSM8112482 RNA-con-in vitro 2 RNA-con-in vitro
- GSE247454 Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer 38 samples shares insufficiency
- GSE222235 DOT1L controls NK cell maturation and lineage integrity 27 samples shares maturation
- GSE299937 Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia 180 samples shares insufficiency
- GSE306583 Developmental trajectory of the mouse transcriptome following placental allopregnanolone insufficiency in the somatosensosry cortex, hippocampus and cerebellum 175 samples shares insufficiency
- GSE281035 PAR3-mediated coordination of hepatocyte proliferation, maturation, and architecture in liver development and regeneration 128 samples shares maturation
- GSE293592 Maternal immune activation delays DNA methylation and physiological maturation of cortical excitatory neurons 106 samples shares maturation
- GSE75769 Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals (ICSI) 103 samples shares maturation
- GSE205438 RNA splicing controls organ-wide maturation of postnatal heart in mice 88 samples shares maturation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.