Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis.
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 2 × WT-male-DRG vs 2 × WT-male-PTX-DRG vs 2 × KO-male-DRGGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasisThe Journal of clinical investigation · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE260669_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1082668 and SRA study SRP492786. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 3 replicated groups read from 11 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8122111 WT-male-DRG1 WT-male-DRG
- GSM8122112 WT-male-DRG2 WT-male-DRG
- GSM8122113 WT-female-DRG3
- GSM8122114 WT-male-PTX-DRG1 WT-male-PTX-DRG
- GSM8122115 WT-male-PTX-DRG2 WT-male-PTX-DRG
- GSM8122116 WT-female-PTX-DRG3
- GSM8122117 KO-male-DRG1 KO-male-DRG
- GSM8122118 KO-male-DRG2 KO-male-DRG
- GSM8122119 KO-female-DRG3
- GSM8122120 KO-male-PTX-DRG1
- GSM8122121 KO-female-PTX-DRG2
- GSE277171 A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance [RNA-seq] 70 samples shares potassium, channel
- GSE222708 Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice. 27 samples shares homeostasis, regulate
- GSE240578 MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis 20 samples shares homeostasis, regulate
- GSE314547 Estradiol disrupts constitutive androstane receptor (CAR)-mediated bile acid homeostasis in a murine model of intrahepatic cholestasis of pregnancy (ICP), and this effect is reversed by CAR ligands 16 samples shares homeostasis, ligand
- GSE302026 Hepatocyte-to-intestinal Stem Cell Remote Communication Regulates Blood Glucose Homeostasis 15 samples shares homeostasis, regulate
- GSE222707 Cancer-cell-secreted miR-9-5p regulates cholesterol homeostasis to promote tumor metastasis [TF TB Rab27AKD miR-9KO] 12 samples shares homeostasis, regulate
- GSE294418 PAN2 Maintains mRNA PolyA Tail Homeostasis and Regulates Translation during Spermiogenesis in Mouse 12 samples shares homeostasis, regulate
- GSE334311 CCR10-Regulated Mucosal Immune Responses Support Restoration of Lung Tissue Homeostasis after SARS-CoV-2 infection. 9 samples shares homeostasis, regulate
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.