Differential gene expression in thalamic postmortem tissue of subjects with obsessive compulsive disorder
RNA-seq (gene expression) · human · 85 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 85 samples: 84 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptomes of higher order thalamic nuclei in obsessive compulsive disorderJournal of affective disorders · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272200_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1135666 and SRA study SRP519772. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 85 sample titles: 84 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8395539 Thalamus, MDMC, CON, Pair 1, HUID 1159
- GSM8395540 Thalamus, MDMC, OCD, Pair 1, HUID 1413
- GSM8395541 Thalamus, MDMC, CON, Pair 10, HUID 1282
- GSM8395542 Thalamus, MDMC, OCD, Pair 10, HUID 13154
- GSM8395543 Thalamus, MDMC, CON, Pair 11, HUID 1834
- GSM8395544 Thalamus, MDMC, OCD, Pair 11, HUID 13169
- GSM8395545 Thalamus, MDMC, CON, Pair 2, HUID 1293
- GSM8395546 Thalamus, MDMC, OCD, Pair 2, HUID 1424
- GSM8395547 Thalamus, MDMC, CON, Pair 3, HUID 13032
- GSM8395548 Thalamus, MDMC, OCD, Pair 3, HUID 1435
- GSM8395549 Thalamus, MDMC, CON, Pair 4, HUID 1092
- GSM8395550 Thalamus, MDMC, OCD, Pair 4, HUID 1505
- GSM8395551 Thalamus, MDMC, CON, Pair 5, HUID 1543
- GSM8395552 Thalamus, MDMC, CON, Pair 6, HUID 1391
- GSM8395553 Thalamus, MDMC, OCD, Pair 6, HUID 13051
- GSM8395554 Thalamus, MDMC, OCD, Pair 6, HUID 1785
- GSM8395555 Thalamus, MDMC, CON, Pair 7, HUID 1083
- GSM8395556 Thalamus, MDMC, OCD, Pair 7, HUID 13022
- GSM8395557 Thalamus, MDMC, CON, Pair 8, HUID 13237
- GSM8395558 Thalamus, MDMC, OCD, Pair 8, HUID 13173
- GSM8395559 Thalamus, MDMC, CON, Pair 9, HUID 1637
- GSM8395560 Thalamus, MDMC, OCD, Pair 9, HUID 13125
- GSM8395561 Thalamus, MDPC, OCD, Pair 1, HUID 1413
- GSM8395562 Thalamus, MDPC, CON, Pair 10, HUID 1282
- GSM8395563 Thalamus, MDPC, OCD, Pair 10, HUID 13154
- GSM8395564 Thalamus, MDPC, CON, Pair 11, HUID 1834
- GSM8395565 Thalamus, MDPC, OCD, Pair 11, HUID 13169
- GSM8395566 Thalamus, MDPC, CON, Pair 2, HUID 1293
- GSM8395567 Thalamus, MDPC, OCD, Pair 2, HUID 1424
- GSM8395568 Thalamus, MDPC, CON, Pair 3, HUID 13032
- GSM8395569 Thalamus, MDPC, OCD, Pair 3, HUID 1435
- GSM8395570 Thalamus, MDPC, CON, Pair 4, HUID 1092
- GSM8395571 Thalamus, MDPC, OCD, Pair 4, HUID 1505
- GSM8395572 Thalamus, MDPC, CON, Pair 5, HUID 1543
- GSM8395573 Thalamus, MDPC, OCD, Pair 5, HUID 1785
- GSM8395574 Thalamus, MDPC, CON, Pair 6, HUID 1391
- GSM8395575 Thalamus, MDPC, OCD, Pair 6, HUID 13051
- GSM8395576 Thalamus, MDPC, CON, Pair 7, HUID 1083
- GSM8395577 Thalamus, MDPC, OCD, Pair 7, HUID 13022
- GSM8395578 Thalamus, MDPC, CON, Pair 8, HUID 13237
+ 45 more — browse all 85 samples with per-sample file links →
- GSE262138 Convergent transcriptomic signatures across brain structures in eating disorders and obsessive compulsive disorder 338 samples shares compulsive, obsessive, disorder
- GSE271268 Gene expression analysis in obsessive-compulsive disorder with and without comorbid neurodevelopmental disorders 28 samples shares compulsive, obsessive, disorder
- GSE328351 Bulk RNA-seq of dorsolateral prefrontal cortex tissue collected during deep brain stimulation neurosurgery in obsessive-compulsive disorder and neurological controls 10 samples shares compulsive, obsessive, disorder
- GSE294621 Vascular-type heterogeneity is associated with differential gene expression profiles of endothelial cells under shear stress 74 samples shares differential
- GSE285352 Alternate isoforms of IRF7 Differentially Regulate Interferon Expression 74 samples shares differential
- GSE287072 Alternative splicing and differential gene expression during changes in endometrial receptivity in patients with recurrent implantation failure 73 samples shares differential
- GSE246920 Differential gene expression induced by combined docetaxel and darolutamide in prostate cancer xenografts 63 samples shares differential
- GSE303049 Investigating Cycle-to-Cycle Variation and the Impact of Endometrial Injury through Differential Gene Expression Analysis 40 samples shares differential
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.