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Neurotensin-Neurotensin Receptor 2 signaling in adipocytes regulates food intake through ceramide metabolism

GSE274164 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/02/05 Platform GPL24247
Summary
Our previous study revealed that NTS suppressed the activity of brown adipose tissue via interactions with NTSR2. In the current study, we found that the depletion of Ntsr2 in the white adipocytes upregulated food intake, while the local treatment of NTS suppressed the food intake.
Published in
Neurotensin-neurotensin receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism
Fu W, Lai Y, Li K et al. · Cell research 2025 · PMID 39748047 · doi:10.1038/s41422-024-01038-8
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Also filed as BioProject PRJNA1145332 and SRA study SRP524712. Searching any of these in the dataset finder brings you back here.

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