RNA-seq for orthotopic lung tumor treated with taurine and proline
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × C57-Control-A vs 3 × C57-Model-A vs 3 × C57-Taurine-A vs 3 × C57-Proline-AGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Taurine and proline promote lung tumour growth by co-regulating Azgp1/mTOR signalling pathwayNPJ precision oncology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE282449_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1188604 and SRA study SRP546552. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8643450 C57-Control-A000 C57-Control-A
- GSM8643451 C57-Control-A001 C57-Control-A
- GSM8643452 C57-Control-A002 C57-Control-A
- GSM8643453 C57-Model-A010 C57-Model-A
- GSM8643454 C57-Model-A018 C57-Model-A
- GSM8643455 C57-Model-A020 C57-Model-A
- GSM8643456 C57-Taurine-A027 C57-Taurine-A
- GSM8643457 C57-Taurine-A028 C57-Taurine-A
- GSM8643458 C57-Taurine-A029 C57-Taurine-A
- GSM8643459 C57-Proline-A038 C57-Proline-A
- GSM8643460 C57-Proline-A039 C57-Proline-A
- GSM8643461 C57-Proline-A048 C57-Proline-A
- GSE262879 Single-cell RNA-sequencing of murine pancreatic tumors derived from the orthotopic transplantation of Smad4 wild-type (WT) or Smad4 knockout (KO) pancreatic ductal adenocarcinoma (PDAC) KPC organoids in nu/nu mice. 18 samples shares orthotopic, rna-seq
- GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples shares rna-seq, lung
- GSE226609 Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure. 20 samples shares rna-seq, lung
- GSE264278 TIme-cource single-cell RNA-seq analysis of bleomycin and LPS-induced lung injury and fibrosis 18 samples shares rna-seq, lung
- GSE297298 Single-cell RNA-sequencing identifies anti-cancer immune phenotypes in the early lung metastatic niche during breast cancer 18 samples shares rna-seq, lung
- GSE306230 RNA-seq of mouse lung tissue after irradiation 12 samples shares rna-seq, lung
- GSE331228 RNA-seq profiling of liver and lung of CLP mice(6h) 12 samples shares rna-seq, lung
- GSE325662 Gene expression profiling of lung tissue from LPS-induced acute lung injury mice treated with Renshen Baidu Powder 9 samples shares treated, lung
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.