← BioTransfer GEO Dataset Finder
GEO series

Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models [mouse_BRAF K499E]

GSE283653 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/03/21 Platform GPL24247
Summary
Performed transcriptomic analysis of BRAF K499E-transfected astrocytes to investigate the molecular basis of BRAF K499E-induced learning and memory deficits.
Published in
Aberrant ERK signaling in astrocytes impairs learning and memory in RASopathy-associated BRAF mutant mouse models
Kang M, Choi J, Han J et al. · The Journal of clinical investigation 2025 · PMID 39964758 · doi:10.1172/JCI176631
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE283653_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1194986 and SRA study SRP549760. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.