LSMEM2, localized at the neuromuscular junction, modulates mitochondrial integration in skeletal muscles
RNA-seq (gene expression) · mouse · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 15 samples: 15 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- LSMEM2, Localized at the Neuromuscular Junction, Modulates Mitochondrial Integration in Skeletal MusclesFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285026_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1201062 and SRA study SRP552924. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 15 sample titles: 15 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8695226 mock_S1_R1_001
- GSM8695227 mock_S2_R1_001
- GSM8695228 mock_S3_R1_001
- GSM8695229 mock_S4_R1_001
- GSM8695230 Cdel_S5_R1_001
- GSM8695231 Cdel_S6_R1_001
- GSM8695232 Cdel_S7_R1_001
- GSM8695233 Cdel_S8_R1_001
- GSM8695234 female_control_1_S14_R1_001
- GSM8695235 female_control_2_S15_R1_001
- GSM8695236 female_control_3_S16_R1_001
- GSM8695237 female_Cdel_1_S17_R1_001
- GSM8695238 female_Cdel_2_S18_R1_001
- GSM8695239 female_Cdel_3_S19_R1_001
- GSM8695240 female_Cdel_4_S20_R1_001
- GSE299537 Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions 16 samples shares neuromuscular, junction, skeletal
- GSE267909 Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance (bulk RNA-Seq) 14 samples shares neuromuscular, junction, skeletal
- GSE267910 Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance (snRNA-Seq) 12 samples shares neuromuscular, junction, skeletal
- GSE294765 A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophy 35 samples shares neuromuscular, junction, skeletal
- GSE280699 The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age [RNA-seq] 78 samples shares mitochondrial, skeletal
- GSE253848 Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation 54 samples shares mitochondrial, skeletal
- GSE325919 Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans 30 samples shares mitochondrial, skeletal
- GSE186648 Skeletal muscle mRNA expression in 25 mice with or without genetic defects of mitochondrial fatty acid oxidation (Acadl and Acadvl knockout) using RNA sequencing. 25 samples shares mitochondrial, skeletal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.