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DNA Damage-Induced Nuclear STING Translocation Orchestrates Innate Immune Activation and Chromatin Remodeling [RNA-Seq]

GSE296538 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2026/01/28 Platform GPL24676
Summary
To define STING’s role in the DNA damage response, we collected STING wild-type (WT) and STING knockout (KO) HeLa cells following 24 hours of BMN673 treatment, as well as non-treated cells. We then performed gene expression profiling analysis using data obtained from RNA-seq dataset across four conditions: STING WT and STING KO cells, with or without 24 hours of BMN673 treatment.
Published in
DNA damage-induced nuclear STING translocation orchestrates innate immune activation and chromatin remodeling
Wang Y, Shen Z, Li L et al. · Genes & diseases 2026 · PMID 41584859 · doi:10.1016/j.gendis.2025.101851
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Also filed as BioProject PRJNA1259928 and SRA study SRP583591. Searching any of these in the dataset finder brings you back here.

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