Expression data of E19.5 placenta from intra-cytoplasmic sperm injection(ICSI)-F1/F2 offspring
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 2 × F1_51F vs 2 × WT_47A vs 2 × WT_47BGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mouse ICSI impairs fertility of male offspring by disruption of fetomaternal toleranceDevelopment (Cambridge, England) · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300654_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1281610 and SRA study SRP594276. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9065863 F1_51D_2
- GSM9065864 F1_51F_2 F1_51F
- GSM9065865 F1_51F_3 F1_51F
- GSM9065866 F1_51G_2
- GSM9065867 F2_52A_4
- GSM9065868 F2_52B_4
- GSM9065869 F2_52D_4
- GSM9065870 F2_52E_4
- GSM9065871 WT_47A_10 WT_47A
- GSM9065872 WT_47A_9 WT_47A
- GSM9065873 WT_47B_10 WT_47B
- GSM9065874 WT_47B_11 WT_47B
- GSE300655 Expression data of E13.5 placenta from intra-cytoplasmic sperm injection(ICSI)-F2 offspring 10 samples shares icsi, intra-cytoplasmic, injection, offspring, placenta, sperm
- GSE300656 Expression data of neonatal brain from male intra-cytoplasmic sperm injection(ICSI)-F2 offspring 8 samples shares icsi, intra-cytoplasmic, injection, offspring, sperm
- GSE75769 Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals (ICSI) 103 samples shares icsi, sperm
- GSE338289 Characterization of molecular changes associated with aging in the mouse cochlear lateral wall [re-analysis of GSE197634] 0 samples shares e19
- GSE220060 Total RNA expression in mouse heart tissues after injections of VEGFA-containing extracellular vessicle, lipidnanoparticles and naked-VEGFA mRNA 18 samples shares injection
- GSE234197 Gene expression profile at single cell level of whole lungs of mice collected from bleomycin or PBS-treated young and old mice at day 14, day 28 and day 60 post injection 12 samples shares injection
- GSE237710 Gene expression profiling of mouse breast tumor tissue after injection of 4T1 therapy-induced senesence derived sEVs 7 samples shares injection
- GSE309843 RNAseq data of frontal cortex of 4 months high fat diet fed WT, AKO, 4 months high fat diet fed conditional human amylin expressing mice followed by vehicle and Tamoxifen injection, and 2 months high fat diet fed WT mice 49 samples shares injection
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.