Expression data of E13.5 placenta from intra-cytoplasmic sperm injection(ICSI)-F2 offspring
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 2 × control_37B vs 2 × ICSI_F2_63A vs 2 × control_63FGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Mouse ICSI impairs fertility of male offspring by disruption of fetomaternal toleranceDevelopment (Cambridge, England) · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300655_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1281613 and SRA study SRP594329. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 3 replicated groups read from 10 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9065875 control_37A3
- GSM9065876 control_37B2 control_37B
- GSM9065877 control_37B3 control_37B
- GSM9065878 ICSI_F2_37D8
- GSM9065879 ICSI_F2_63A1 ICSI_F2_63A
- GSM9065880 ICSI_F2_63A2 ICSI_F2_63A
- GSM9065881 ICSI_F2_63B2
- GSM9065882 ICSI_F2_63D2
- GSM9065883 control_63F1 control_63F
- GSM9065884 control_63F2 control_63F
- GSE300654 Expression data of E19.5 placenta from intra-cytoplasmic sperm injection(ICSI)-F1/F2 offspring 12 samples shares icsi, intra-cytoplasmic, injection, offspring, placenta, sperm
- GSE300656 Expression data of neonatal brain from male intra-cytoplasmic sperm injection(ICSI)-F2 offspring 8 samples shares icsi, intra-cytoplasmic, injection, offspring, sperm
- GSE75769 Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals (ICSI) 103 samples shares icsi, sperm
- GSE244114 Effect of polyIC administration on gene expression in decidual tissues of E13.5 mice 8 samples shares e13
- GSE262468 Gene expression profile of FACS sorted cranial neural crest cells from E12.5-E13.5 mouse embryonic head 4 samples shares e13
- GSE244115 Effect of polyIC administration on gene expression in decidual NK cells of E13.5 mice 4 samples shares e13
- GSE268575 Determine the role of ALK5 signaling in murine brain pericytes at embryonic day E13.5 24 samples shares e13
- GSE292542 RNA seq of activated CD8 T cells of WT and Card11 mutant mice(E134G/K215M) 18 samples shares e13
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.