GEO series
Liver RNA-seq from obese mice following Roux-en-Y gastric bypass or sham surgery under chow or high-fat diet conditions
GSE303852
Mus musculus
Expression profiling by high throughput sequencing
20 samples
2026/02/25
GPL24247
Summary
This study investigates how Roux-en-Y gastric bypass (RYGB) and high-fat diet (HFD) influence liver gene expression in mice. RNA sequencing was performed on liver samples from diet-induced obese male C57BL/6 mice that underwent either RYGB or sham surgery, followed by an 8-week post-operative period on either chow or HFD. Raw sequencing reads (FASTQ) and gene-level count data are provided to support investigation of RYGB- and diet-associated transcriptional changes in hepatic tissue.
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Paper (PMID 41598416) ↗
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