Liver RNA-seq from obese mice following Roux-en-Y gastric bypass or sham surgery under chow or high-fat diet conditions
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × liver, sham chow, vs 5 × liver, RYGB chow, vs 5 × liver, sham HFD, vs 5 × liver, RYGB HFD,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Analysis of Roux-en-Y Gastric Bypass and High-Fat Feeding Reveals Hepatic Transcriptome Reprogramming: Ironing out the DetailsJournal of clinical medicine · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303852_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1297769 and SRA study SRP604052. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9136928 liver, sham chow, 1 liver, sham chow,
- GSM9136929 liver, sham chow, 2 liver, sham chow,
- GSM9136930 liver, sham chow, 3 liver, sham chow,
- GSM9136931 liver, sham chow, 4 liver, sham chow,
- GSM9136932 liver, sham chow, 5 liver, sham chow,
- GSM9136933 liver, RYGB chow, 1 liver, RYGB chow,
- GSM9136934 liver, RYGB chow, 2 liver, RYGB chow,
- GSM9136935 liver, RYGB chow, 3 liver, RYGB chow,
- GSM9136936 liver, RYGB chow, 4 liver, RYGB chow,
- GSM9136937 liver, RYGB chow, 5 liver, RYGB chow,
- GSM9136938 liver, sham HFD, 1 liver, sham HFD,
- GSM9136939 liver, sham HFD, 2 liver, sham HFD,
- GSM9136940 liver, sham HFD, 3 liver, sham HFD,
- GSM9136941 liver, sham HFD, 4 liver, sham HFD,
- GSM9136942 liver, sham HFD, 5 liver, sham HFD,
- GSM9136943 liver, RYGB HFD, 1 liver, RYGB HFD,
- GSM9136944 liver, RYGB HFD, 2 liver, RYGB HFD,
- GSM9136945 liver, RYGB HFD, 3 liver, RYGB HFD,
- GSM9136946 liver, RYGB HFD, 4 liver, RYGB HFD,
- GSM9136947 liver, RYGB HFD, 5 liver, RYGB HFD,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.