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Stiffness-related mitochondria transfer promotes tumor progression through metabolic reprogramming

GSE311895 Mus musculus Expression profiling by high throughput sequencing 18 samples 2025/12/04 GPL24247
Summary
The physical properties of the tumor microenvironment (TME), particularly extracellular matrix stiffness, are key factors influencing cancer progression. While intercellular mitochondrial transfer is emerging as a vital mechanism for tumor metabolic adaptation, its potential interaction with TME mechanical properties remains unexplored.
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