GEO series
Bulk RNAseq analysis of wildtype and Pim1-/- macrophages
GSE335106
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/06/15
GPL17021
Summary
PIM1 is a serine/threonine kinase that modulates immune responses and cellular metabolism. To examine the function of PIM1 in macrophage gene expression, peritoneal macrophages were isolated from wild-type and Pim1-/- mice. They were treated with 20 μg/mL oxidized low-density lipoprotein for 8 hours. Total RNA was extracted and analyzed using bulk RNA sequencing to compare gene expression profiles and identify differentially regulated pathways between wild-type and Pim1-/- macrophages.
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