Gene expression changes in ventricular tissues were identified through RNA sequencing analysis of a mouse model of cardiac hypertrophic remodeling induced by angiotensin II (Ang II)
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × Con vs 4 × Ang II vs 4 × Ang II_FIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE337111_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1484069 and SRA study SRP713907. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9848324 Con_1 Con
- GSM9848325 Con_2 Con
- GSM9848326 Con_3 Con
- GSM9848327 Con_4 Con
- GSM9848328 Ang II_1 Ang II
- GSM9848329 Ang II_2 Ang II
- GSM9848330 Ang II_3 Ang II
- GSM9848331 Ang II_4 Ang II
- GSM9848332 Ang II_FI_1 Ang II_FI
- GSM9848333 Ang II_FI_2 Ang II_FI
- GSM9848334 Ang II_FI_3 Ang II_FI
- GSM9848335 Ang II_FI_4 Ang II_FI
- GSE285383 CCL5 promotes angiotensin II-induced cardiac remodeling through regulation of platelet-driven M2 macrophage polarization 12 samples shares angiotensin, remodeling, cardiac, induced
- GSE255932 Role of the catalytic beta subunit of calcineurin (Ppp3cb) in angiotensin II induced vascular changes 24 samples shares angiotensin, changes, induced
- GSE267256 Bulk RNA-seq analysis reveals the crucial role of Collagen triplex helix repeat containing-1 (Cthrc1) cardiac fibroblasts for ventricular remodeling after myocardial infarction 17 samples shares ventricular, remodeling, cardiac
- GSE283472 Resolvin E1/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II-Induced Hypertensive Mice 15 samples shares angiotensin, remodeling, induced
- GSE277624 CD163+ cardiac macrophages attenuate pressure overload-induced left ventricular systolic dysfunction via interleukin-10 10 samples shares ventricular, cardiac, induced
- GSE284286 Cardiomyocyte-specific LARP6 overexpression prevents Angiotensin II-induced myocardial dysfunction and interstitial fibrosis 50 samples shares angiotensin, induced
- GSE338380 Hepatocyte angiotensinogen deletion protects against Western diet-induced adiposity and hepatic steatosis under thermoneutral housing 48 samples shares angiotensin, induced
- GSE306718 Macrophage Cluster of Differentiation 163 promotes post-infarction cardiac repair and preserves left ventricular function via osteopontin 37 samples shares ventricular, cardiac
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.