Drug, across the briefings

Lapatinib across 19 cancers

Lapatinib appears in 19 of the briefings; its FDA label names 1 of those diseases.

DiseaseFDA labelOpen Targets stage, on which geneTrialsActive
Breast cancerlabel names diseaseapproved on ERBB21734
Anal cancerapproved on EGFR——
Bladder cancerapproved on ERBB280
Cervical cancerapproved on ERBB2, EGFR20
Cholangiocarcinomaapproved on ERBB240
Colorectal cancerapproved on EGFR, ERBB280
Cutaneous squamous cell carcinomaapproved on EGFR——
Endometrial cancerapproved on ERBB220
Esophageal cancerapproved on ERBB2, EGFR61
Gallbladder cancerapproved on ERBB2, EGFR40
Gastric cancerapproved on ERBB2101
Glioblastomaapproved on EGFR71
Head and neck cancerapproved on EGFR121
Lung cancerapproved on EGFR, ERBB270
Nasopharyngeal carcinomaapproved on EGFR——
Osteosarcomaapproved on ERBB2——
Pancreatic cancerapproved on EGFR30
Small intestine cancerapproved on ERBB2——
Vulvar cancerapproved on EGFR——

The label column is the briefing's openFDA stage: a label whose Indications and Usage names the disease. The Open Targets column is the furthest clinical stage recorded for the drug against any gene on that briefing's target list, in any indication. Trials are ClinicalTrials.gov interventional studies naming the drug and the disease, from the briefing's trials stage; a dash means the briefing did not search this drug in that disease (it searches the drugs Open Targets lists against its own genes), which is not the same as none. Salt forms, biosimilar suffixes and formulation words are merged by the same rule the briefings use.