GEO series
Gene expression profile at single cell level of murine glioblastomas treated with and without anti-CSF-1R inhibitors
GSE229409
Mus musculus
Expression profiling by high throughput sequencing
10 samples
2024/08/10
GPL24247
Summary
Anti-CSF-1R treatment results in rapid regression of murne proneural glioblastoma models. However, the microenvironment response to treatment results in fibrosis that can promote tumor recurrence. We investigated the single-cell transcriptional profile of murine glioblastomas before and after treatment with an anti-CSF-1R inhibitor to determine the cause of fibrotic treatment response.
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Paper (PMID 39255775) ↗
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